Eva Kudová Group
CS

Joint laboratory

In collaboration with the Second Faculty of Medicine at Charles University in Prague, we have established the joint laboratory, a hub dedicated to advancing interdisciplinary research at the interface of medicinal chemistry and neuroscience.

This dynamic partnership brings together expertise in organic synthesis, design of novel drug-like compounds, and cutting-edge neuroscientific methods, integrated with in vivo neurofunctional assessment.

Our goal is to develop innovative chemical tools and therapeutics capable of selectively modulating and visualizing neural processes, thereby deepening our understanding of synaptic dynamics, signaling pathways, and cellular responses in living neuronal systems.

By seamlessly combining organic chemistry, molecular biology, and real-time imaging with neuroscientific exploration, the joint laboratory drives forward transformative insights into brain function, paving the way for next-generation diagnostics and therapeutic strategies.

Joint laboratory team members


  • Jan Daněk (Second Faculty of Medicine, Charles University in Prague) – Ph.D. student, Thesis: Investigation of the effects of newly-synthetised neuroactive steroids on neuronal activity in animal models of acute and chronic epilepsy
  • Nikola Vršková (Second Faculty of Medicine, Charles University in Prague) – Ph.D. student, Thesis: Mechanisms of etiopathogenesis of focal cortical dysplasia type I
  • Šárka Danačíková (Second Faculty of Medicine, Charles University in Prague) – Ph.D. student, Thesis: Development of in vitro methods for personalized diagnostics of neuropsychiatric diseases
  • Pavla Hosenseidlová (Faculty of Science, Charles University in Prague) – Master´s student, Thesis: Mechanisms of neurosteroid action in epilepsy
  • Petra Mrózková (Second Faculty of Medicine, Charles University in Prague) – postdoc, patch clamp experiments
  • Jan Svoboda (Second Faculty of Medicine, Charles University in Prague) – postdoc, in vivo cerebral blood flow experiments
  • Lucie Bínová (Second Faculty of Medicine, Charles University in Prague) – technician
  • Dominika Jiráková (Second Faculty of Medicine, Charles University in Prague) – technician
  • Kristýna Pěničková (Second Faculty of Medicine, Charles University in Prague) – technician